100% prepayment by SWIFT or Stripe. Larger orders quoted by volume; freight quoted on request
Functional ingredient·
Plant cell culture extract
·Japan

Rose Callus Stem Cell Extract Powder

An extract of Damask rose (Rosa damascena) cells grown as callus in pure culture by a Japanese producer, from roses of Bulgarian origin. This page covers the food-grade powder for supplements, drinks and confectionery; a liquid grade in butylene glycol serves skincare. The producer identified the polyphenols gallic acid and rutin in the extract.

Minimum order
MOQ price
5 g
Free sample
Ships from Japan 1-1.5 weeks after paymentFreight quoted on requestSWIFT or Stripe
Rose Callus Stem Cell Extract Powder
Specification · lot CoA

Key figures at a glance

Your lot's CoA governs
Plant
Rosa damascena
Damask rose of Bulgarian origin
Source material
Callus culture
cultured rose cells, not harvested petals
Food grade
Powder
for supplements, drinks, jellies, confectionery
Cosmetic grade
Liquid
in butylene glycol, for lotions, creams, masks
Polyphenols identified
Gallic acid, rutin
qualitative, no content specification
Supplied from
Japan
Japanese plant cell culture producer
Lot-specific values are measured and reported for every lot. Natural raw materials move with season and harvest, so we give you the figures of the lot you actually receive, not one fixed number.
What it is
Extract of Damask rose (Rosa damascena) callus cells propagated in pure culture by a Japanese producer; the roses are of Bulgarian origin. Food-grade powder on this page; a liquid cosmetic grade in butylene glycol is quoted separately
Form
Powder for food use. Appearance, carrier and particle size are stated in the producer specification supplied with your quotation
Shelf life
Packing
Lead time
Ships from Japan 1-1.5 weeks after payment when stock is available; otherwise timing is confirmed in your quotation
Terms
100% prepayment by SWIFT or Stripe. Larger orders quoted by volume; freight quoted on request
Price and documents

Request a price, specification or sample

Tell us what you are developing and which documents you need. We reply from Japan within one working day with the product specification, SDS and the CoA of the current lot.

Free sample for registered companies developing a product
Volume quotation for orders above the minimum
Specification, SDS and lot CoA on request

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Process

How it is made

The extract is not made from harvested petals. The producer takes callus cells from Damask rose, propagates them in pure culture and obtains the extract from the cultured cells. Because the material is grown in culture, supply does not depend on harvest season or climate. Culture medium, drying and carrier details are given in the specification supplied with your quotation.

A callus is a mass of undifferentiated plant cells, the kind a plant forms where it is wounded, and its cells can still develop into any part of the plant. This is what plant stem cell means on an ingredient label: the material is an extract made from cultured callus cells, not a preparation of living cells.

Plant selection

Step 1 · Rosa damascena

Damask rose of Bulgarian origin

Callus cells

Step 2 · undifferentiated

Rose cells that can still develop into any part of the plant

Pure culture

Step 3 · in vitro

Cells propagated in culture, independent of season and climate

Extraction

Step 4 · cultured cells

Extract obtained from the propagated cells

Two grades

Step 5 · powder or liquid

Powder for food use; liquid extract in butylene glycol for cosmetics

Specification

Specification at a glance

The grade on this page. Other grades, where available, are specified on request.

Identity and composition

  • What it is: extract of Damask rose callus cells propagated in pure culture; food-grade powder
  • Plant: Rosa damascena (Damask rose), Rosaceae; roses of Bulgarian origin
  • Source material: callus (undifferentiated) cells, not field-harvested flowers
  • Polyphenols: gallic acid and rutin identified by the producer (qualitative; no content specification)
  • Grades: powder for food use; liquid extract in butylene glycol for cosmetics
  • INCI name, cosmetic grade: Rosa Damascena Callus Culture Extract
  • Supplied from: Japan, by a Japanese plant cell culture producer

Process and peptide profile

  • Process: callus cells taken from Damask rose, propagated in pure culture, extract obtained from the cultured cells
  • Supply: cultured material, so availability does not depend on harvest season or climate (producer)
  • Food applications listed by the producer: drinks, supplements, jellies, confectionery and other foods
  • Cosmetic applications listed by the producer (liquid grade): lotions, essences, creams, face masks and packs, cosmetic soap, BB cream

Analytical specification

  • Appearance, moisture, carrier and particle size: stated in the producer specification, supplied with your quotation

Contaminants, microbiology and safety

  • Heavy metals, arsenic and microbiology: stated in the specification and the lot Certificate of Analysis, supplied with your quotation
  • Allergens and GMO status: confirmed with the specification
  • Halal and kosher: not on file; checked per order

Shelf life, storage and packing

  • Shelf life and storage: stated in the specification supplied with your quotation
  • Packing and MOQ: confirmed in your quotation
  • Documents: specification, SDS and lot Certificate of Analysis are confirmed with your quotation
  • Samples: on request for registered companies developing a product
SPEC
Product specification, PDF. On request through the form.
CoA
Certificate of Analysis. One for every lot, ships with the goods.
SDS
Safety Data Sheet. On request through the form.

Example lot values are published in the developer's guide below. They are an example, not a specification; your lot's CoA governs.

Direct from Japan

Working with us

A Japanese trading company selling directly to brand owners and contract manufacturers. No distributor layer between you and the documents.

A CoA for the lot you receive

Every shipment travels with the Certificate of Analysis of its own lot, with the measured values and the full safety panel.

Start at the minimum order

A small first order lets you run a pilot batch before committing to bulk. Larger volumes are quoted by volume and delivery terms.

Free sample

For registered companies developing a product. Tell us the format you plan and we will say honestly what to expect.

Ships from Japan in 1-1.5 weeks

After payment is received. Freight quoted on request. Specification and SDS before you order, CoA with the goods.

Buyer's checklist

What to ask any supplier

If you are comparing ingredients for a new SKU, these questions separate one material from another quickly.

Powder for ingestibles, or the liquid grade for skincare?

This page is the food-grade powder. The same rose callus extract exists as a liquid in butylene glycol for lotions, creams and masks, under the INCI name Rosa Damascena Callus Culture Extract; it is quoted separately.

Is a plant cell culture extract accepted as a food ingredient in your market?

Rules differ by market. In the EU, food produced from plant cell or tissue culture is one of the categories covered by the novel food definition of Regulation (EU) 2015/2283. The status check for ingestible use sits with the brand owner or importer; we supply the producer documents it needs.

How will you word stem cell on your label?

The material is an extract of cultured plant cells, not living stem cells, so describe it as a rose callus culture extract. Under EU rules, regeneration or wound-healing claims fall outside the cosmetic definition, and health claims on foods must be authorised. Plan the wording with your regulatory counsel.

What daily amount or use level will you formulate?

The producer documents we hold give no reference daily amount for the powder and no use level for the liquid. The concentration in the producer's cell-culture test is a test condition, not dosage guidance. Ask for the producer's recommendation with your quotation.

Which in vitro data do you need for your dossier?

The producer's work covers aquaporin-3 and COX-2 in skin cells, polyphenols with free-radical scavenging, and a scratch assay on human keratinocytes. All are cell-culture experiments, not studies in people. Tell us which descriptions you need and we will send them with the documents.

Do you need halal or kosher documentation?

Not on file. Halal documentation is often requested for supplements in the UAE and other Muslim-majority markets; ask us and we will check with the producer what can be issued for your order.

For product developers

The developer's guide

What each component is, what the processing changes, and what published research on the raw material has examined. No health claims; references on request.

Rose callus extract: the Damask rose, grown as cells

Plant cell culture is an established route to cosmetic actives: by 2018 more than 50 cosmetic products based on plant cell culture extracts were on the market, and the first food supplement ingredients from plant cell cultures were made at production scale (sources at the end of this guide). Rose Callus Stem Cell Extract brings the Damask rose (Rosa damascena) into that category. Instead of extracting harvested petals, the producer propagates rose callus cells in pure culture and extracts the cultured cells, so the material does not depend on the rose harvest.

Where it is used

The powder is a food raw material for ingestible beauty and wellness formulas: the producer lists drinks, supplements, jellies and confectionery. In a beauty-from-within line it sits naturally next to Rose Placenta Extract Powder, a culture extract from another tissue of the same rose species, and a protein base such as Fish Collagen Tripeptide or Fish Elastin Peptide.

One extract, two grades

The same rose callus extract is made as a liquid in butylene glycol for skincare: lotions, essences, creams, face masks and packs, cosmetic soap and BB cream, under the INCI name Rosa Damascena Callus Culture Extract. A brand can carry one rose active across a supplement and a skincare product. The liquid grade is quoted separately; tell us the intended form when you ask.

What you receive

MOQ, price, packing and shelf life are confirmed in your quotation, together with the producer specification and the document set for your market. Samples are free for registered companies developing a product. Our own OEM line at Tomioka Plant makes finished capsules, tablets and stick packs from 5,000 units per SKU; we check the powder's fit for your format with the sample.

We will help you choose the form and packaging for your brand.

What a rose callus extract is, and what has been studied

Callus and plant stem cells

Plants have a strong regenerative ability: they repair damaged tissue and can even grow into new plants. In 1902 the Austrian botanist Gottlieb Haberlandt explained that callus tissue can form from fully developed plant cells and suggested that every plant cell can regenerate a whole plant. In the plant, stem cells sit in the meristems, and callus, the cell mass a plant forms at a wound, is counted among the secondary meristems. In culture, callus cells renew themselves and can be directed to form shoots and roots [1].

The producer of this extract builds on two properties of these cells: self-renewal, dividing while staying undifferentiated, and the capacity to differentiate into different tissues.

How plant cell culture ingredients are made

The general method starts with a chosen plant part, which is sterilised and induced to form callus on a nutrient medium. The callus is subcultured repeatedly, the line with the best growth is selected, and production moves to liquid culture and bioreactors under controlled conditions; the cells are then disrupted or extracted to release their compounds [1]. Compared with field-grown plants, cell cultures avoid pesticide residues and the differences between growth stages, plant ages and organs, and they do not depend on climate [2]. By 2018 more than 50 cosmetic products based on plant cell culture extracts had reached the market, most of them made in suspension culture, and the first food supplement ingredients from plant cell cultures were produced at production scale [3].

What stem cell does and does not mean

The term is used loosely across the beauty market. In most cases a product labelled plant stem cell contains an extract of cultured plant cells, not living stem cells: cultured plant cells would not survive formulation and preservatives, and their size and rigid walls keep them out of the skin. For that reason, cosmetic claims around these ingredients are usually framed as antioxidant or protective effects. In the EU, claims of regeneration or wound healing fall outside the legal definition of a cosmetic product under Regulation (EC) No 1223/2009 [1]. The material on this page is an extract of cultured rose cells and is best described that way on labels and in marketing.

Polyphenols of the Damask rose

An analysis of Damask rose leaves and stems reported gallic acid among the phenolics and rutin among the flavonoids [4], and gallic acid is one of the main phenolic constituents of rose hips across several Rosa species [5]. The producer has identified both gallic acid and rutin in the rose callus extract. These are qualitative findings: the extract has no specified polyphenol content.

What the producer's laboratory work examined

The producer's technical documents for the two grades describe the following cell-culture work. These are producer data, provided for evaluation; they describe in vitro experiments, not results in people, and they are not claims for a finished product.

  • Aquaporin-3. The relative level of aquaporin-3 (AQP3) mRNA, a water-channel protein of the skin's outer layer, was measured in skin cells with and without the extract.
  • COX-2. The relative intensity of cyclooxygenase-2, an enzyme linked to irritation responses, was measured in skin cells with and without the extract.
  • Polyphenols and free radicals. The polyphenol profile of the extract was analysed and its free-radical scavenging was tested.
  • Scratch assay. A scratch was made in a single layer of cultured human keratinocytes (HaCaT); growth medium containing 5 ppm extract was added, and the open area was measured at three points after 18 hours against an untreated control.

Full descriptions of these experiments, including the results reported by the producer, are available to registered companies on request.

Regulatory notes for formulators

The powder is the producer's food-use grade, and the liquid grade carries an INCI name for cosmetics. For ingestible use outside Japan, the status of a plant cell culture extract is checked by the brand owner or importer. In the EU, Regulation (EU) 2015/2283 lists food produced from plant cell or tissue culture among the categories of its novel food definition, which applies unless significant consumption before 15 May 1997 is shown [6]. Statements about the effect of a finished product are the brand owner's responsibility under the rules of the destination market.

Sources

  1. J Cosmet Dermatol 2026, review: stem cells in cosmetic applications. doi:10.1111/jocd.70866
  2. Plants (Basel) 2025, review: plant stem cells in the cosmetic industry. doi:10.3390/plants14030433
  3. Appl Microbiol Biotechnol 2018, mini review: plant cell culture technology in the cosmetics and food industries. doi:10.1007/s00253-018-9279-8
  4. Life (Basel) 2022: phytochemical evaluation of Rosa damascena pruning residues. doi:10.3390/life12020273
  5. J Sci Food Agric 2019: fruit phytochemical composition of 21 accessions of five Rosa species. doi:10.1002/jsfa.9842
  6. Regulation (EU) 2015/2283 on novel foods, Article 3(2)(a)(vi).

Product facts: the producer's technical documents for the food and cosmetic grades and the producer's product information. Summaries are provided to registered companies on request.

FAQ

Before you order

What is rose callus stem cell extract?

It is an extract of Damask rose (Rosa damascena) cells grown as callus, an undifferentiated plant cell mass, in pure culture. The roses are of Bulgarian origin and the cells are propagated by a Japanese producer, so supply does not depend on the flower harvest. This page covers the food-grade powder; a liquid grade in butylene glycol serves skincare under the INCI name Rosa Damascena Callus Culture Extract.

Does the extract contain living stem cells?

No. Plant stem cell is the market term for extracts made from cultured, undifferentiated plant cells. This material is an extract of cultured rose callus cells, not a preparation of living cells. Describe it on labels as a rose callus culture extract and keep claims within the rules of your market: under EU cosmetic law, regeneration or wound-healing claims fall outside the cosmetic definition.

What are the MOQ, price and lead time for Rose Callus Stem Cell Extract Powder from Iizuka Shoukai?

MOQ, price, packing and shelf life are confirmed in your quotation; larger orders are quoted by volume and freight is quoted on request. Goods ship from Japan 1-1.5 weeks after payment when stock is available; otherwise timing is confirmed in the quotation. Payment is 100% prepayment by SWIFT or Stripe. Iizuka Shoukai also offers OEM finished-product manufacturing in capsules, tablets and sticks at our Tomioka Plant in Gunma, from 5,000 units per SKU.

What is the difference between the powder and the liquid grade?

The powder is the producer's food-use grade for supplements, drinks, jellies and confectionery. The liquid grade is the same rose callus extract in butylene glycol for lotions, essences, creams, face masks, soap and BB cream, with the INCI name Rosa Damascena Callus Culture Extract. Tell us which form you need; each is quoted separately.

What data and documents come with the material?

The producer's technical documents describe in vitro work on aquaporin-3 and COX-2 in skin cells, polyphenols with free-radical scavenging, and a scratch assay on human keratinocytes; these are cell-culture data, not claims. Gallic acid and rutin were identified qualitatively. The specification, SDS and lot Certificate of Analysis are confirmed with your quotation. Halal and kosher documentation is not on file and is checked per order.
Rose Callus Stem Cell Extract Powder

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Rose Callus Stem Cell Extract Powder

An extract of Damask rose (Rosa damascena) cells grown as callus in pure culture by a Japanese producer, from roses of Bulgarian origin. This page covers the food-grade powder for supplements, drinks and confectionery; a liquid grade in butylene glycol serves skincare. The producer identified the polyphenols gallic acid and rutin in the extract.
Request specs
CATEGORY
Plant cell culture extract
MOQ
MOQ price

Rose callus extract: the Damask rose, grown as cells

Plant cell culture is an established route to cosmetic actives: by 2018 more than 50 cosmetic products based on plant cell culture extracts were on the market, and the first food supplement ingredients from plant cell cultures were made at production scale (sources at the end of this guide). Rose Callus Stem Cell Extract brings the Damask rose (Rosa damascena) into that category. Instead of extracting harvested petals, the producer propagates rose callus cells in pure culture and extracts the cultured cells, so the material does not depend on the rose harvest.

Where it is used

The powder is a food raw material for ingestible beauty and wellness formulas: the producer lists drinks, supplements, jellies and confectionery. In a beauty-from-within line it sits naturally next to Rose Placenta Extract Powder, a culture extract from another tissue of the same rose species, and a protein base such as Fish Collagen Tripeptide or Fish Elastin Peptide.

One extract, two grades

The same rose callus extract is made as a liquid in butylene glycol for skincare: lotions, essences, creams, face masks and packs, cosmetic soap and BB cream, under the INCI name Rosa Damascena Callus Culture Extract. A brand can carry one rose active across a supplement and a skincare product. The liquid grade is quoted separately; tell us the intended form when you ask.

What you receive

MOQ, price, packing and shelf life are confirmed in your quotation, together with the producer specification and the document set for your market. Samples are free for registered companies developing a product. Our own OEM line at Tomioka Plant makes finished capsules, tablets and stick packs from 5,000 units per SKU; we check the powder's fit for your format with the sample.

We will help you choose the form and packaging for your brand.

Price and documents

Request a price, specification or sample

What a rose callus extract is, and what has been studied

Callus and plant stem cells

Plants have a strong regenerative ability: they repair damaged tissue and can even grow into new plants. In 1902 the Austrian botanist Gottlieb Haberlandt explained that callus tissue can form from fully developed plant cells and suggested that every plant cell can regenerate a whole plant. In the plant, stem cells sit in the meristems, and callus, the cell mass a plant forms at a wound, is counted among the secondary meristems. In culture, callus cells renew themselves and can be directed to form shoots and roots [1].

The producer of this extract builds on two properties of these cells: self-renewal, dividing while staying undifferentiated, and the capacity to differentiate into different tissues.

How plant cell culture ingredients are made

The general method starts with a chosen plant part, which is sterilised and induced to form callus on a nutrient medium. The callus is subcultured repeatedly, the line with the best growth is selected, and production moves to liquid culture and bioreactors under controlled conditions; the cells are then disrupted or extracted to release their compounds [1]. Compared with field-grown plants, cell cultures avoid pesticide residues and the differences between growth stages, plant ages and organs, and they do not depend on climate [2]. By 2018 more than 50 cosmetic products based on plant cell culture extracts had reached the market, most of them made in suspension culture, and the first food supplement ingredients from plant cell cultures were produced at production scale [3].

What stem cell does and does not mean

The term is used loosely across the beauty market. In most cases a product labelled plant stem cell contains an extract of cultured plant cells, not living stem cells: cultured plant cells would not survive formulation and preservatives, and their size and rigid walls keep them out of the skin. For that reason, cosmetic claims around these ingredients are usually framed as antioxidant or protective effects. In the EU, claims of regeneration or wound healing fall outside the legal definition of a cosmetic product under Regulation (EC) No 1223/2009 [1]. The material on this page is an extract of cultured rose cells and is best described that way on labels and in marketing.

Polyphenols of the Damask rose

An analysis of Damask rose leaves and stems reported gallic acid among the phenolics and rutin among the flavonoids [4], and gallic acid is one of the main phenolic constituents of rose hips across several Rosa species [5]. The producer has identified both gallic acid and rutin in the rose callus extract. These are qualitative findings: the extract has no specified polyphenol content.

What the producer's laboratory work examined

The producer's technical documents for the two grades describe the following cell-culture work. These are producer data, provided for evaluation; they describe in vitro experiments, not results in people, and they are not claims for a finished product.

  • Aquaporin-3. The relative level of aquaporin-3 (AQP3) mRNA, a water-channel protein of the skin's outer layer, was measured in skin cells with and without the extract.
  • COX-2. The relative intensity of cyclooxygenase-2, an enzyme linked to irritation responses, was measured in skin cells with and without the extract.
  • Polyphenols and free radicals. The polyphenol profile of the extract was analysed and its free-radical scavenging was tested.
  • Scratch assay. A scratch was made in a single layer of cultured human keratinocytes (HaCaT); growth medium containing 5 ppm extract was added, and the open area was measured at three points after 18 hours against an untreated control.

Full descriptions of these experiments, including the results reported by the producer, are available to registered companies on request.

Regulatory notes for formulators

The powder is the producer's food-use grade, and the liquid grade carries an INCI name for cosmetics. For ingestible use outside Japan, the status of a plant cell culture extract is checked by the brand owner or importer. In the EU, Regulation (EU) 2015/2283 lists food produced from plant cell or tissue culture among the categories of its novel food definition, which applies unless significant consumption before 15 May 1997 is shown [6]. Statements about the effect of a finished product are the brand owner's responsibility under the rules of the destination market.

Sources

  1. J Cosmet Dermatol 2026, review: stem cells in cosmetic applications. doi:10.1111/jocd.70866
  2. Plants (Basel) 2025, review: plant stem cells in the cosmetic industry. doi:10.3390/plants14030433
  3. Appl Microbiol Biotechnol 2018, mini review: plant cell culture technology in the cosmetics and food industries. doi:10.1007/s00253-018-9279-8
  4. Life (Basel) 2022: phytochemical evaluation of Rosa damascena pruning residues. doi:10.3390/life12020273
  5. J Sci Food Agric 2019: fruit phytochemical composition of 21 accessions of five Rosa species. doi:10.1002/jsfa.9842
  6. Regulation (EU) 2015/2283 on novel foods, Article 3(2)(a)(vi).

Product facts: the producer's technical documents for the food and cosmetic grades and the producer's product information. Summaries are provided to registered companies on request.

Rose Callus Stem Cell Extract Powder
Got Questions? We've Got Answers

Frequently Asked Questions

  • What is rose callus stem cell extract?

    It is an extract of Damask rose (Rosa damascena) cells grown as callus, an undifferentiated plant cell mass, in pure culture. The roses are of Bulgarian origin and the cells are propagated by a Japanese producer, so supply does not depend on the flower harvest. This page covers the food-grade powder; a liquid grade in butylene glycol serves skincare under the INCI name Rosa Damascena Callus Culture Extract.

  • Does the extract contain living stem cells?

    No. Plant stem cell is the market term for extracts made from cultured, undifferentiated plant cells. This material is an extract of cultured rose callus cells, not a preparation of living cells. Describe it on labels as a rose callus culture extract and keep claims within the rules of your market: under EU cosmetic law, regeneration or wound-healing claims fall outside the cosmetic definition.

  • What are the MOQ, price and lead time for Rose Callus Stem Cell Extract Powder from Iizuka Shoukai?

    MOQ, price, packing and shelf life are confirmed in your quotation; larger orders are quoted by volume and freight is quoted on request. Goods ship from Japan 1-1.5 weeks after payment when stock is available; otherwise timing is confirmed in the quotation. Payment is 100% prepayment by SWIFT or Stripe. Iizuka Shoukai also offers OEM finished-product manufacturing in capsules, tablets and sticks at our Tomioka Plant in Gunma, from 5,000 units per SKU.

  • What is the difference between the powder and the liquid grade?

    The powder is the producer's food-use grade for supplements, drinks, jellies and confectionery. The liquid grade is the same rose callus extract in butylene glycol for lotions, essences, creams, face masks, soap and BB cream, with the INCI name Rosa Damascena Callus Culture Extract. Tell us which form you need; each is quoted separately.

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