A torula yeast extract powder specified at not less than 20.0% total glutathione by DTNB-HPLC, made in Japan from pure-cultured torula yeast. It is 100% yeast extract with no carrier: a pale yellow to pale yellowish-brown powder with a slight yeast odour and a 2-year shelf life.
Tell us what you are developing and which documents you need. We reply from Japan within one working day with the product specification, SDS and the CoA of the current lot.
The producer's manufacturing control sheet describes one continuous flow from extraction of torula yeast to X-ray inspection of the packed powder. After the yeast cells are separated, the extract goes through an oxidation step, clarification and deodorisation, and is then concentrated, heat-sterilised and dried.
Step 1 · torula yeast
The extract is taken from pure-cultured torula yeast
Step 2 · centrifugation
Yeast cells are removed and the extract separated
Step 3 · oxidation reaction
A defined oxidation step in the producer's flow
Step 4 · filtration
The extract is clarified and deodorised
Step 5 · heat
Concentrated, then heat-sterilised for microbial control
Step 6 · powder
Dried to a pale yellow powder
Step 7 · 40 mesh
Magnet trap at 0.5 tesla on the 10 kg line
Step 8 · X-ray
Stainless steel test pieces: 1.0 mm for 10 kg, 0.7 mm for 1 kg packs
The grade on this page. Other grades, where available, are specified on request.
Example lot values are published in the developer's guide below. They are an example, not a specification; your lot's CoA governs.
A Japanese trading company selling directly to brand owners and contract manufacturers. No distributor layer between you and the documents.
Every shipment travels with the Certificate of Analysis of its own lot, with the measured values and the full safety panel.
A small first order lets you run a pilot batch before committing to bulk. Larger volumes are quoted by volume and delivery terms.
For registered companies developing a product. Tell us the format you plan and we will say honestly what to expect.
After payment is received. Freight quoted on request. Specification and SDS before you order, CoA with the goods.
If you are comparing ingredients for a new SKU, these questions separate one material from another quickly.
The specification guarantees not less than 20.0% total glutathione by DTNB-HPLC. It does not split reduced and oxidised glutathione, so declare from the total or from the result for your lot.
In Japan, reduced glutathione is on the list of substances used only as pharmaceuticals, so Japanese foods declare this ingredient as yeast extract. Check which ingredient name and glutathione content statement your market allows before you design the label.
Neither certificate is in our document set for this product. In the UAE, supplements need a halal certificate.
The producer positions this 20% grade mainly for drinks and jellies, and it is also used in tablets and capsules. A 15% grade with dextrin exists for tablets and granules; ask if your process needs it.
The extract is deodorised in process but keeps a slight characteristic yeast odour. Test it in your actual flavour system, especially in clear drinks.
The powder comes in 1 kg aluminium laminate bags or a single 10 kg polyethylene bag. Tell us your batch size and we quote the matching packing.
What each component is, what the processing changes, and what published research on the raw material has examined. No health claims; references on request.
Glutathione Yeast Extract Powder 20% is a yeast extract, not an isolated glutathione. It is made in Japan from pure-cultured torula yeast and specified by its total glutathione content: not less than 20.0% by DTNB-HPLC. The extract is the whole ingredient, 100% yeast extract with no carrier.
Glutathione occurs naturally in yeast cells. In this extract it sits with related cysteine-containing peptides, which the producer groups under the name cysteine peptides.
In the producer's formula examples from Japan, this grade sits in beauty drinks and jellies next to vitamin C and collagen. The 15% grade appears in tablets with vitamin C and collagen, and in powdered sports drinks with whey protein and glutamine.
This page describes the 20% grade. The producer also makes a 15% grade that contains dextrin, positioned for tablets, capsules, granules and powdered drinks; its specification is sent on request.
If you want a finished product rather than the raw material, our plant in Gunma, Japan fills sticks and aluminium pouches. Send your formula and target pack for an OEM quotation. For a collagen partner in the same beauty formula, see Fish Collagen Tripeptide; for another yeast-based ingredient, see Yeast Protein 80%.
Glutathione is a tripeptide built from three amino acids, glutamate, cysteine and glycine, and written gamma-glutamyl-cysteinyl-glycine. The gamma link between glutamate and cysteine is unusual for a peptide, and the thiol (SH) group of cysteine is the reactive part of the molecule. It is the most abundant low-molecular-weight thiol in animal cells (J Nutr 2004).
Glutathione exists as a reduced form (GSH) and as an oxidised form, glutathione disulfide (GSSG), in which two molecules are joined through their sulfur atoms. The GSH/GSSG pair is the main redox couple in animal cells. The body makes glutathione itself in two enzyme steps from glutamate, cysteine and glycine, and cysteine availability is one of the factors that regulate this synthesis (J Nutr 2004).
Glutathione takes part in the reduction of oxidants and in the conjugation of electrophilic compounds, and it helps keep the redox balance of the cell (Mol Aspects Med 2009). When hydrogen peroxide is reduced by the enzyme glutathione peroxidase, GSH is converted to GSSG; glutathione reductase then recycles GSSG back to GSH.
Glutathione is present in many everyday foods. A US analysis of the foods in a national food frequency questionnaire found dairy products, cereals and breads generally low in glutathione, fruits and vegetables moderate to high, and freshly prepared meats relatively high. Frozen foods kept levels close to fresh ones, while most other processing and preservation caused large losses (Nutr Cancer 1992).
Glutathione is the most abundant non-protein thiol in living organisms. Industrial fermentative production of glutathione uses Saccharomyces cerevisiae and Candida utilis, the species known as torula yeast (Appl Microbiol Biotechnol 2004). In the United States, dried torula yeast is one of the yeasts that may be used in food under 21 CFR 172.896, with a limit on folic acid content. That section covers dried yeast; a yeast extract is a separate ingredient, so check its status in your own market.
A formula can take glutathione in two ways: as an isolated glutathione, or as a yeast extract in which glutathione is the specified active. This product is the second kind. In Japan the difference is regulatory: reduced glutathione is on the list of substances used exclusively as pharmaceuticals, so foods there use glutathione-containing yeast extracts and declare them as yeast extract. Outside Japan, the ingredient name and any statement of glutathione content follow the rules of the destination market.
Whether glutathione taken by mouth raises glutathione levels in the body has been studied in randomised trials. These trials used isolated glutathione, not this yeast extract.
A randomised, double-blind, placebo-controlled trial in 40 healthy adults measured urinary markers of oxidative stress (F2-isoprostanes and 8-OHdG) and glutathione in red blood cells. doi:10.1089/acm.2010.0716
A randomised, double-blind, placebo-controlled trial in 54 non-smoking adults measured glutathione in whole blood, red blood cells, plasma, lymphocytes and cells from the inner cheek. doi:10.1007/s00394-014-0706-z
The two trials differed in length and dose and reached different conclusions on body glutathione, so oral uptake is still discussed. Neither tested this ingredient, and no effect is claimed for it here.
Start at the minimum order. Free sample. Specification, SDS and lot CoA on request.
Request a sample or quotationGlutathione Yeast Extract Powder 20% is a yeast extract, not an isolated glutathione. It is made in Japan from pure-cultured torula yeast and specified by its total glutathione content: not less than 20.0% by DTNB-HPLC. The extract is the whole ingredient, 100% yeast extract with no carrier.
Glutathione occurs naturally in yeast cells. In this extract it sits with related cysteine-containing peptides, which the producer groups under the name cysteine peptides.
In the producer's formula examples from Japan, this grade sits in beauty drinks and jellies next to vitamin C and collagen. The 15% grade appears in tablets with vitamin C and collagen, and in powdered sports drinks with whey protein and glutamine.
This page describes the 20% grade. The producer also makes a 15% grade that contains dextrin, positioned for tablets, capsules, granules and powdered drinks; its specification is sent on request.
If you want a finished product rather than the raw material, our plant in Gunma, Japan fills sticks and aluminium pouches. Send your formula and target pack for an OEM quotation. For a collagen partner in the same beauty formula, see Fish Collagen Tripeptide; for another yeast-based ingredient, see Yeast Protein 80%.
Glutathione is a tripeptide built from three amino acids, glutamate, cysteine and glycine, and written gamma-glutamyl-cysteinyl-glycine. The gamma link between glutamate and cysteine is unusual for a peptide, and the thiol (SH) group of cysteine is the reactive part of the molecule. It is the most abundant low-molecular-weight thiol in animal cells (J Nutr 2004).
Glutathione exists as a reduced form (GSH) and as an oxidised form, glutathione disulfide (GSSG), in which two molecules are joined through their sulfur atoms. The GSH/GSSG pair is the main redox couple in animal cells. The body makes glutathione itself in two enzyme steps from glutamate, cysteine and glycine, and cysteine availability is one of the factors that regulate this synthesis (J Nutr 2004).
Glutathione takes part in the reduction of oxidants and in the conjugation of electrophilic compounds, and it helps keep the redox balance of the cell (Mol Aspects Med 2009). When hydrogen peroxide is reduced by the enzyme glutathione peroxidase, GSH is converted to GSSG; glutathione reductase then recycles GSSG back to GSH.
Glutathione is present in many everyday foods. A US analysis of the foods in a national food frequency questionnaire found dairy products, cereals and breads generally low in glutathione, fruits and vegetables moderate to high, and freshly prepared meats relatively high. Frozen foods kept levels close to fresh ones, while most other processing and preservation caused large losses (Nutr Cancer 1992).
Glutathione is the most abundant non-protein thiol in living organisms. Industrial fermentative production of glutathione uses Saccharomyces cerevisiae and Candida utilis, the species known as torula yeast (Appl Microbiol Biotechnol 2004). In the United States, dried torula yeast is one of the yeasts that may be used in food under 21 CFR 172.896, with a limit on folic acid content. That section covers dried yeast; a yeast extract is a separate ingredient, so check its status in your own market.
A formula can take glutathione in two ways: as an isolated glutathione, or as a yeast extract in which glutathione is the specified active. This product is the second kind. In Japan the difference is regulatory: reduced glutathione is on the list of substances used exclusively as pharmaceuticals, so foods there use glutathione-containing yeast extracts and declare them as yeast extract. Outside Japan, the ingredient name and any statement of glutathione content follow the rules of the destination market.
Whether glutathione taken by mouth raises glutathione levels in the body has been studied in randomised trials. These trials used isolated glutathione, not this yeast extract.
A randomised, double-blind, placebo-controlled trial in 40 healthy adults measured urinary markers of oxidative stress (F2-isoprostanes and 8-OHdG) and glutathione in red blood cells. doi:10.1089/acm.2010.0716
A randomised, double-blind, placebo-controlled trial in 54 non-smoking adults measured glutathione in whole blood, red blood cells, plasma, lymphocytes and cells from the inner cheek. doi:10.1007/s00394-014-0706-z
The two trials differed in length and dose and reached different conclusions on body glutathione, so oral uptake is still discussed. Neither tested this ingredient, and no effect is claimed for it here.
It is a yeast extract made in Japan from pure-cultured torula yeast and specified at not less than 20.0% total glutathione by DTNB-HPLC. The powder is 100% yeast extract with no carrier, pale yellow to pale yellowish-brown, with a slight yeast odour. Iizuka Shoukai, a trading company in Gunma, Japan, supplies it with the producer's specification and ships from Japan 1-1.5 weeks after payment.
The minimum order is 1 kg, one aluminium laminate bag, at 490 USD/kg, and registered companies can request a free 20 g evaluation sample. Payment is 100% prepayment by SWIFT or Stripe. Freight is quoted on request, and larger orders, including 10 kg bags, are quoted by volume.
The specification guarantees not less than 20.0% total glutathione, measured by DTNB-HPLC. It sets the total only and does not split reduced and oxidised glutathione; the producer's process includes an oxidation step. A 15% grade with dextrin, positioned for tablets and granules, is specified on request.
The producer's manufacturing control sheet lists 100% yeast extract from torula yeast, no allergenic raw materials, no genetically modified crops and no bovine-derived materials, and confirms compliance with Japan's positive list for agricultural chemical residues. Halal and kosher certificates are not in our document set for this product.
