Freeze-dried yellow sap from the stems of ashitaba (Angelica keiskei), standardized to min. 8.0% total chalcones by HPLC. The main chalcones are xanthoangelol and 4-hydroxyderricin. Made in Japan for capsules, tablets and granules.
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Tell us what you are developing and which documents you need. We reply from Japan within one working day with the product specification, SDS and the CoA of the current lot.
The chalcones in this powder come from one part of the plant: the yellow sap that seeps from cut ashitaba stems. The sap is filtered and heat-sterilized, then sterilized again and freeze-dried in Japan, and the powder is made to a specification of min. 8.0% total chalcones by HPLC.
Step 1 · stems
Cut at the right stage of growth
Step 2 · yellow sap
Collected as it seeps from the cut surface
Step 3 · filtration
Plant residue removed
Step 4 · high temperature and pressure
First sterilization of the sap
Step 5 · in Japan
Repeated before drying
Step 6 · in Japan
Sap dried to a yellow powder
Step 7 · HPLC
Total chalcones, moisture, microbiology
The grade on this page. Other grades, where available, are specified on request.
Example lot values are published in the developer's guide below. They are an example, not a specification; your lot's CoA governs.
A Japanese trading company selling directly to brand owners and contract manufacturers. No distributor layer between you and the documents.
Every shipment travels with the Certificate of Analysis of its own lot, with the measured values and the full safety panel.
A small first order lets you run a pilot batch before committing to bulk. Larger volumes are quoted by volume and delivery terms.
For registered companies developing a product. Tell us the format you plan and we will say honestly what to expect.
After payment is received. Freight quoted on request. Specification and SDS before you order, CoA with the goods.
If you are comparing ingredients for a new SKU, these questions separate one material from another quickly.
Ask for the method and for what "total chalcones" includes. Here the specification sets min. 8.0% total chalcones by HPLC, with xanthoangelol and 4-hydroxyderricin as the main chalcones.
Ashitaba ingredients are made in different ways: freeze-dried sap, solvent extracts of leaves and stems, or dried whole plant. A chalcone percentage means different things for each, so compare the starting material, not only the number.
The carrier goes on your ingredient list. This powder uses cyclodextrin, a cyclic oligosaccharide, as carrier.
Some markets treat ashitaba sap as a novel food or permit only listed plant ingredients. Check the status for your product category before launch; registration of the finished product sits with the brand owner or importer.
Heavy metals, arsenic and pesticide residues are analyzed by an external laboratory at least once a year, and moisture and microbiology are part of the specification. Ask which results the lot CoA reports.
What each component is, what the processing changes, and what published research on the raw material has examined. No health claims; references on request.
Ashitaba Chalcone Powder is a concentrate made from the yellow sap of Angelica keiskei stems. It is standardized to min. 8.0% total chalcones by HPLC, which suits formulations that call for a defined chalcone content rather than a whole-plant powder.
The product documents list capsules, tablets and granules as applications. The powder is yellow, has a characteristic aroma and should be kept away from moisture during processing and in the finished pack.
Need finished capsules rather than powder? We also make OEM supplements in Japan: see OEM supplements. For background on the plant, read our ashitaba guide for formulators; another Japanese polyphenol ingredient is Red Pine Needle Extract (Concentrate).
To discuss price, volume or your application, or to request the specification or a sample, use the request form on this page.
Ashitaba, Angelica keiskei (Miq.) Koidz., is a perennial herb of the Apiaceae family from Japan. Its aerial parts are consumed as a health food, and the plant is sold in health foods and as an additive in health drinks (review: Kil et al., Archives of Pharmacal Research, 2017).
Chalcones are a subgroup of flavonoids, the large family of plant polyphenols. In ashitaba they are found in the sticky yellow sap that seeps from a cut stem. Ten or more chalcones have been identified in this sap, and xanthoangelol and 4-hydroxyderricin are the most abundant.
Both are prenylated chalcones, that is, chalcones that carry prenyl side chains. A 2024 review of 55 articles names them as the two main chalcones of the plant and summarizes the pharmacology reported for them (Wahyuni et al., Heliyon, 2024). In this product, total chalcones are measured by HPLC and set at min. 8.0% in the specification.
Besides chalcones, research on the plant has identified other flavonoids, coumarins, phenolics, acetylenes and terpenes (Kil et al., 2017). The chalcone 4,4'-dimethoxychalcone (DMC) has also been identified in Angelica keiskei (Carmona-Gutierrez et al., Nature Communications, 2019); its level in this powder is not specified.
Ashitaba ingredients come in three main kinds: dried whole-plant or leaf powders, solvent extracts of leaves and stems, and concentrates of the yellow sap such as this powder. They differ in starting material, carrier and chalcone content, so specifications are best compared line by line.
The reviews above summarize laboratory, animal and human research on Angelica keiskei and its chalcones. That research was not conducted on this lot and is not a claim for this ingredient; the statements a finished product may carry are set by the rules of its market.
Start at the minimum order. Free sample. Specification, SDS and lot CoA on request.
Request a sample or quotationAshitaba Chalcone Powder is a concentrate made from the yellow sap of Angelica keiskei stems. It is standardized to min. 8.0% total chalcones by HPLC, which suits formulations that call for a defined chalcone content rather than a whole-plant powder.
The product documents list capsules, tablets and granules as applications. The powder is yellow, has a characteristic aroma and should be kept away from moisture during processing and in the finished pack.
Need finished capsules rather than powder? We also make OEM supplements in Japan: see OEM supplements. For background on the plant, read our ashitaba guide for formulators; another Japanese polyphenol ingredient is Red Pine Needle Extract (Concentrate).
To discuss price, volume or your application, or to request the specification or a sample, use the request form on this page.
Ashitaba, Angelica keiskei (Miq.) Koidz., is a perennial herb of the Apiaceae family from Japan. Its aerial parts are consumed as a health food, and the plant is sold in health foods and as an additive in health drinks (review: Kil et al., Archives of Pharmacal Research, 2017).
Chalcones are a subgroup of flavonoids, the large family of plant polyphenols. In ashitaba they are found in the sticky yellow sap that seeps from a cut stem. Ten or more chalcones have been identified in this sap, and xanthoangelol and 4-hydroxyderricin are the most abundant.
Both are prenylated chalcones, that is, chalcones that carry prenyl side chains. A 2024 review of 55 articles names them as the two main chalcones of the plant and summarizes the pharmacology reported for them (Wahyuni et al., Heliyon, 2024). In this product, total chalcones are measured by HPLC and set at min. 8.0% in the specification.
Besides chalcones, research on the plant has identified other flavonoids, coumarins, phenolics, acetylenes and terpenes (Kil et al., 2017). The chalcone 4,4'-dimethoxychalcone (DMC) has also been identified in Angelica keiskei (Carmona-Gutierrez et al., Nature Communications, 2019); its level in this powder is not specified.
Ashitaba ingredients come in three main kinds: dried whole-plant or leaf powders, solvent extracts of leaves and stems, and concentrates of the yellow sap such as this powder. They differ in starting material, carrier and chalcone content, so specifications are best compared line by line.
The reviews above summarize laboratory, animal and human research on Angelica keiskei and its chalcones. That research was not conducted on this lot and is not a claim for this ingredient; the statements a finished product may carry are set by the rules of its market.

It is freeze-dried yellow sap from the stems of ashitaba (Angelica keiskei), with cyclodextrin as carrier, standardized to min. 8.0% total chalcones by HPLC. The main chalcones are xanthoangelol and 4-hydroxyderricin. Iizuka Shoukai supplies it from Japan as a bulk ingredient for capsules, tablets and granules.
The minimum order is 1 kg at 2,650 USD/kg; larger orders are quoted by volume, and freight is quoted on request. Payment is 100% prepayment by SWIFT or Stripe, and orders ship from Japan 1-1.5 weeks after payment. Registered companies developing a product can request a free 10 g sample.
The specification sets total chalcones at min. 8.0% (HPLC), moisture at max. 8.0%, total plate count at max. 3,000 CFU/g with coliforms negative, heavy metals at max. 30 ppm, arsenic at max. 2 ppm (ICP-MS) and pesticide residues not detected (GC-MS). Heavy metals, arsenic and pesticide residues are analyzed by an external laboratory at least once a year. The specification is available before you order; the lot CoA and SDS are available on request.
The product documents list capsules, tablets and granules as applications. It is a yellow powder with a characteristic aroma. Shelf life is 3 years from production when stored in a cool, dark place away from direct sunlight and moisture.