100% prepayment by SWIFT or Stripe. Tiered large-volume quotes and freight on request
Functional ingredient·
Cognitive and circulatory health
·Japan

Ginkgo Biloba Leaf Extract

Standardized Ginkgo biloba leaf extract powder, 24% flavone glycosides and 6% terpene lactones, ginkgolic acid 1 ppm or less, five times below the 5 ppm norm. Japanese-origin leaf option with full raw-material traceability. Supplied in bulk in 1 kg and 10 kg packs.

1 kg
Minimum order
1,520 USD/kg
MOQ price
20 g
Free sample
Ships from Japan 1-1.5 weeks after paymentFreight quoted on requestSWIFT or Stripe
Ginkgo Biloba Leaf Extract
Specification · lot CoA

Key figures at a glance

Your lot's CoA governs
Flavone glycosides
min. 24.0%
24/6 specification
Total terpene lactones
min. 6.0%
ginkgolides A, B, C and bilobalide
Ginkgolic acid
max. 1 ppm
5x stricter than the 5 ppm norm
Bilobalide
min. 2.5%
reference value on the CoA
Heavy metals
max. 10 ppm
arsenic max. 2 ppm
Total viable count
max. 300 cfu/g
coliforms negative
Lot-specific values are measured and reported for every lot. Natural raw materials move with season and harvest, so we give you the figures of the lot you actually receive, not one fixed number.
What it is
Standardized extract of Ginkgo biloba leaves, 100% ginkgo leaf extract, built to the 24/6 specification. Declared on labels as "ginkgo leaf extract"; no bovine-derived material, no GMO or allergen labeling required
Form
Yellowish-brown to brown powder with a characteristic odor and bitter taste
Shelf life
2 years from manufacture, unopened at room temperature; airtight container away from heat and humidity, protect from moisture after opening
Packing
1 kg and 10 kg packs
Lead time
Ships from Japan 1-1.5 weeks after payment; Certificate of Analysis on request
Terms
100% prepayment by SWIFT or Stripe. Tiered large-volume quotes and freight on request
Price and documents

Request a price, specification or sample

Tell us what you are developing and which documents you need. We reply from Japan within one working day with the product specification, SDS and the CoA of the current lot.

Free sample for registered companies developing a product
Volume quotation for orders above the minimum
Specification, SDS and lot CoA on request

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Process

How it is made

The extract is produced through integrated in-house manufacturing from specially cultivated, carefully selected ginkgo leaves, with a verified Japanese-origin leaf option for full raw-material traceability. The process is designed to keep the flavonoid and terpenoid fractions in balance while stripping ginkgolic acid down to the 1 ppm level.

Ginkgolic acids are the alkylphenol fraction of ginkgo leaf associated with allergic skin reactions. In this extract they are almost entirely removed and controlled to 1 ug/g (1 ppm) or less, five times stricter than the 5 ppm limit normally applied to pharmaceutical-grade ginkgo. This is one of the defining quality features of the material.
Specification

Specification at a glance

The grade on this page. Other grades, where available, are specified on request.

Identity and composition

  • What it is: standardized extract of Ginkgo biloba leaves, supplied as a powder
  • Composition: ginkgo leaf extract 100%
  • Origin: integrated in-house manufacturing; verified Japanese-origin leaf option for full traceability
  • Label declaration: ginkgo leaf extract
  • Appearance: yellowish-brown to brown powder with a characteristic odor and bitter taste
  • Identification: conforms (color reaction)
  • Allergen / GMO: no allergen or genetically-modified labeling required; contains no bovine-derived material

Process and peptide profile

  • Standardization: 24/6: flavone glycosides 24.0% or more, total terpene lactones 6.0% or more
  • Terpene lactones, reference values on the CoA: ginkgolide A 1.2% or more, ginkgolide B 0.8% or more, ginkgolide C 1.0% or more, bilobalide 2.5% or more
  • Characteristic constituents: flavonoids (quercetin, isorhamnetin, kaempferol), biflavones (ginkgetin, bilobetin), terpenoids (ginkgolides A/B/C) and bilobalide
  • Reference intake: 60-240 mg/day as ginkgo extract (Japan Health and Nutrition Food Association standard)

Analytical specification

  • Flavone glycosides: 24.0% or more
  • Total terpene lactones: 6.0% or more
  • Loss on drying: 5% or less
  • Residue on ignition: 2% or less

Contaminants, microbiology and safety

  • Ginkgolic acid: 1 ppm (1 ug/g) or less
  • Heavy metals: 10 ppm or less
  • Arsenic: 2 ppm or less
  • Total viable count: 300 cfu/g or less
  • Coliforms: negative

Shelf life, storage and packing

  • Shelf life: 2 years from manufacture, unopened at room temperature
  • Storage: airtight container away from heat and humidity; after opening, protect from moisture and use promptly
  • Packing: 1 kg and 10 kg packs
  • MOQ: 1 kg
  • Documents: product specification and MSDS available now; Certificate of Analysis on request
  • Samples: free 20 g samples on request for registered companies
SPEC
Product specification, PDF. On request through the form.
CoA
Certificate of Analysis. One for every lot, ships with the goods.
SDS
Safety Data Sheet. On request through the form.

Example lot values are published in the developer's guide below. They are an example, not a specification; your lot's CoA governs.

Direct from Japan

Working with us

A Japanese trading company selling directly to brand owners and contract manufacturers. No distributor layer between you and the documents.

A CoA for the lot you receive

Every shipment travels with the Certificate of Analysis of its own lot, with the measured values and the full safety panel.

Start at the minimum order

A small first order lets you run a pilot batch before committing to bulk. Larger volumes are quoted by volume and delivery terms.

Free sample

For registered companies developing a product. Tell us the format you plan and we will say honestly what to expect.

Ships from Japan in 1-1.5 weeks

After payment is received. Freight quoted on request. Specification and SDS before you order, CoA with the goods.

Buyer's checklist

What to ask any supplier

If you are comparing ingredients for a new SKU, these questions separate one material from another quickly.

For product developers

The developer's guide

What each component is, what the processing changes, and what published research on the raw material has examined. No health claims; references on request.

A standardized Ginkgo biloba leaf extract, refined for purity

This is a standardized extract of Ginkgo biloba leaves, supplied as a powder and built to the established 24/6 specification: not less than 24.0% flavone glycosides and not less than 6.0% total terpene lactones. It concentrates the two compound families that make ginkgo leaf distinctive - flavonoids and terpenoids - which are not found together in this way in other plants. Research first documented in Germany about three decades ago identified bioactivities linked to these compounds, including effects on cerebral function and peripheral circulation, and standardized ginkgo leaf extract has since become one of the most widely used botanical functional materials worldwide.

Ginkgo biloba itself is a tree of exceptional resilience. The species appeared roughly 250 million years ago, survived the ice ages, and individual trees can live for thousands of years - a botanical 'living fossil' prized in Japan, where it accounts for a large share of street trees and turns brilliant gold each autumn.

Labeling and formulation

  • Declared on finished-product labels as 'ginkgo leaf extract'
  • Contains no bovine-derived material
  • No genetically-modified or allergen labeling required
  • Reference intake: 60-240 mg/day as ginkgo extract (per the Japan Health and Nutrition Food Association standard)

Clinical and standardization evidence for Ginkgo biloba leaf extract

Standardized Ginkgo biloba leaf extracts defined by roughly 24% flavone glycosides and 6% terpene lactones - the EGb 761-type extract - are the form behind ginkgo's clinical record. The European Union herbal monograph (EMA) recognizes a refined dry extract quantified to 22-27% ginkgo flavone glycosides (quercetin, kaempferol, isorhamnetin) and 5-7% terpene lactones (ginkgolides A/B/C 2.8-3.4%, bilobalide 2.6-3.2%), with ginkgolic acids less than 5 ppm. This material sits in that same standardization band, at a stricter 1 ppm ginkgolic-acid level.

Mechanism: antioxidant flavonoids plus PAF-antagonist terpenoids

The two active fractions work through different routes. The flavonoids (for example quercetin) carry most of the antioxidant and free-radical-scavenging activity, while the terpene lactones (ginkgolides) act as platelet-activating-factor (PAF) antagonists; in a neuronal cell model, both fractions contributed to protection against beta-amyloid toxicity (Shi et al., Chemico-Biological Interactions, 2009).

Cognition in mild dementia (meta-analyses)

Several meta-analyses of randomized, placebo-controlled trials report that the standardized extract at 240 mg/day is superior to placebo for cognition, activities of daily living and global clinical assessment in cognitive impairment and dementia, with tolerability comparable to placebo (Gauthier and Schlaefke, Clinical Interventions in Aging, 2014; Tan et al., Journal of Alzheimer's Disease, 2015; Riepe et al., World Journal of Biological Psychiatry, 2025). This evidence describes the standardized extract as studied in trials; it is not a claim about any particular finished product, and permitted claims depend on the destination market.

Standardization matters because the category is widely adulterated

Independent analyses repeatedly find ginkgo supplements adulterated - flavonol aglycones or rutin and quercetin added to inflate the measured flavonol content. In one study only 3 of 14 commercial finished products were authentic (Ma et al., Phytomedicine, 2016); a USDA-led fingerprinting study likewise flagged rutin- and quercetin-spiked products (Harnly et al., Journal of AOAC International, 2012). Authentic, traceable material removes the single largest quality-assurance risk in the category - failed identity testing and recalls.

Why tight ginkgolic-acid control matters

Ginkgolic acids are allergenic alkylphenols, which is why pharmacopeial and pharmaceutical practice caps them at 5 ppm or less in ginkgo extract. Holding them to 1 ppm or less puts this material in the safest tier and clears even the strictest market and pharmaceutical limits.

Beyond human supplements

Standardized ginkgo leaf extract is also recognized outside human supplements: a dried Ginkgo biloba leaf extract is authorized in the EU as a feed additive for cats and dogs, supporting the growing pet cognitive-health category.

FAQ

Before you order

What is this Ginkgo biloba leaf extract standardized to?

It is standardized to 24.0% or more flavone glycosides and 6.0% or more total terpene lactones (ginkgolides A, B, C and bilobalide) - the established 24/6 specification used for clinically studied standardized ginkgo extracts. Ginkgolic acid is controlled to 1 ppm or less.

Why does ginkgolic acid 1 ppm or less matter?

Ginkgolic acids are allergenic alkylphenols linked to skin sensitization. The usual pharmaceutical limit is 5 ppm or less; this extract is held to 1 ppm or less, five times stricter, so it passes the strictest market and pharmaceutical limits and lowers contact-allergy risk.

How is it supplied and what is its regulatory status?

It is supplied as a bulk raw material in 1 kg and 10 kg packs. In Japan it fits the FFC route for memory and cognition; in the United States it is used as a dietary-supplement ingredient. In the EU and UK, ginkgo leaf dry extract is frequently regulated as a herbal medicine and the food-supplement route is restricted, so confirm classification for your market. Reference intake is 60-240 mg/day.

How do I know it is authentic and not adulterated?

Authenticity is the core of this material. Product specifications (flavone glycosides, terpene lactones, ginkgolic acid) and an MSDS are available now, with a Certificate of Analysis on request; a Japanese-origin leaf option adds full traceability - valuable in a category where independent studies find a large share of products adulterated.

What are pricing, samples and lead time?

Price is 1,520 USD/kg for the 1 kg minimum order; larger volumes are quoted by volume and freight is quoted on request. Free 20 g samples, a Certificate of Analysis and tiered large-volume quotes are available on request. Orders ship from Japan 1-1.5 weeks after payment is received.
Ginkgo Biloba Leaf Extract

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1,520 USD/kg
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Ginkgo Biloba Leaf Extract

Standardized Ginkgo biloba leaf extract powder, 24% flavone glycosides and 6% terpene lactones, ginkgolic acid 1 ppm or less, five times below the 5 ppm norm. Japanese-origin leaf option with full raw-material traceability. Supplied in bulk in 1 kg and 10 kg packs.
Request specs
CATEGORY
Cognitive and circulatory health
MOQ
1 kg
MOQ price
1,520 USD/kg

A standardized Ginkgo biloba leaf extract, refined for purity

This is a standardized extract of Ginkgo biloba leaves, supplied as a powder and built to the established 24/6 specification: not less than 24.0% flavone glycosides and not less than 6.0% total terpene lactones. It concentrates the two compound families that make ginkgo leaf distinctive - flavonoids and terpenoids - which are not found together in this way in other plants. Research first documented in Germany about three decades ago identified bioactivities linked to these compounds, including effects on cerebral function and peripheral circulation, and standardized ginkgo leaf extract has since become one of the most widely used botanical functional materials worldwide.

Ginkgo biloba itself is a tree of exceptional resilience. The species appeared roughly 250 million years ago, survived the ice ages, and individual trees can live for thousands of years - a botanical 'living fossil' prized in Japan, where it accounts for a large share of street trees and turns brilliant gold each autumn.

Labeling and formulation

  • Declared on finished-product labels as 'ginkgo leaf extract'
  • Contains no bovine-derived material
  • No genetically-modified or allergen labeling required
  • Reference intake: 60-240 mg/day as ginkgo extract (per the Japan Health and Nutrition Food Association standard)
Price and documents

Request a price, specification or sample

Clinical and standardization evidence for Ginkgo biloba leaf extract

Standardized Ginkgo biloba leaf extracts defined by roughly 24% flavone glycosides and 6% terpene lactones - the EGb 761-type extract - are the form behind ginkgo's clinical record. The European Union herbal monograph (EMA) recognizes a refined dry extract quantified to 22-27% ginkgo flavone glycosides (quercetin, kaempferol, isorhamnetin) and 5-7% terpene lactones (ginkgolides A/B/C 2.8-3.4%, bilobalide 2.6-3.2%), with ginkgolic acids less than 5 ppm. This material sits in that same standardization band, at a stricter 1 ppm ginkgolic-acid level.

Mechanism: antioxidant flavonoids plus PAF-antagonist terpenoids

The two active fractions work through different routes. The flavonoids (for example quercetin) carry most of the antioxidant and free-radical-scavenging activity, while the terpene lactones (ginkgolides) act as platelet-activating-factor (PAF) antagonists; in a neuronal cell model, both fractions contributed to protection against beta-amyloid toxicity (Shi et al., Chemico-Biological Interactions, 2009).

Cognition in mild dementia (meta-analyses)

Several meta-analyses of randomized, placebo-controlled trials report that the standardized extract at 240 mg/day is superior to placebo for cognition, activities of daily living and global clinical assessment in cognitive impairment and dementia, with tolerability comparable to placebo (Gauthier and Schlaefke, Clinical Interventions in Aging, 2014; Tan et al., Journal of Alzheimer's Disease, 2015; Riepe et al., World Journal of Biological Psychiatry, 2025). This evidence describes the standardized extract as studied in trials; it is not a claim about any particular finished product, and permitted claims depend on the destination market.

Standardization matters because the category is widely adulterated

Independent analyses repeatedly find ginkgo supplements adulterated - flavonol aglycones or rutin and quercetin added to inflate the measured flavonol content. In one study only 3 of 14 commercial finished products were authentic (Ma et al., Phytomedicine, 2016); a USDA-led fingerprinting study likewise flagged rutin- and quercetin-spiked products (Harnly et al., Journal of AOAC International, 2012). Authentic, traceable material removes the single largest quality-assurance risk in the category - failed identity testing and recalls.

Why tight ginkgolic-acid control matters

Ginkgolic acids are allergenic alkylphenols, which is why pharmacopeial and pharmaceutical practice caps them at 5 ppm or less in ginkgo extract. Holding them to 1 ppm or less puts this material in the safest tier and clears even the strictest market and pharmaceutical limits.

Beyond human supplements

Standardized ginkgo leaf extract is also recognized outside human supplements: a dried Ginkgo biloba leaf extract is authorized in the EU as a feed additive for cats and dogs, supporting the growing pet cognitive-health category.

Ginkgo Biloba Leaf Extract
Got Questions? We've Got Answers

Frequently Asked Questions

  • What is this Ginkgo biloba leaf extract standardized to?

    It is standardized to 24.0% or more flavone glycosides and 6.0% or more total terpene lactones (ginkgolides A, B, C and bilobalide) - the established 24/6 specification used for clinically studied standardized ginkgo extracts. Ginkgolic acid is controlled to 1 ppm or less.

  • Why does ginkgolic acid 1 ppm or less matter?

    Ginkgolic acids are allergenic alkylphenols linked to skin sensitization. The usual pharmaceutical limit is 5 ppm or less; this extract is held to 1 ppm or less, five times stricter, so it passes the strictest market and pharmaceutical limits and lowers contact-allergy risk.

  • How is it supplied and what is its regulatory status?

    It is supplied as a bulk raw material in 1 kg and 10 kg packs. In Japan it fits the FFC route for memory and cognition; in the United States it is used as a dietary-supplement ingredient. In the EU and UK, ginkgo leaf dry extract is frequently regulated as a herbal medicine and the food-supplement route is restricted, so confirm classification for your market. Reference intake is 60-240 mg/day.

  • How do I know it is authentic and not adulterated?

    Authenticity is the core of this material. Product specifications (flavone glycosides, terpene lactones, ginkgolic acid) and an MSDS are available now, with a Certificate of Analysis on request; a Japanese-origin leaf option adds full traceability - valuable in a category where independent studies find a large share of products adulterated.

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