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Akoya Pearl Powder

A rare source of calcium and conchiolin. Supports skin radiance, bone strength and hormonal balance. Ideal for premium nutricosmetic and anti-aging applications.
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CATEGORY
Amino acids
PACKAGE
1 kg
PRICE
on request

Akoya Pearl Powder for wholesale buyers

Akoya Pearl Powder is sourced from genuine Japanese Akoya pearls (Pinctada fucata oyster) harvested in Japan. The manufacturing process involves carefully separating the pearl from its shell nucleus and thoroughly cleaning the nacre (mother-of-pearl) layer to ensure purity. The pearls are then pulverized and ultra-fine milled (micronized) into a soft, high grade powder. This process is done without any calcination (no high-heat treatment), which helps preserve the pearls’ natural nutrients. The final product is 100% pure Akoya pearl powder with no carriers or additives – it is not mixed with any excipients, ensuring the ingredient’s integrity.

NUTRITIONAL & FUNCTIONAL PROPETIES OF AKOYA PEARL POWDER

  • Composition
    Akoya Pearl Powder consists predominantly of calcium compounds (calcium carbonate) and contains a unique pearl protein called conchiolin. Conchiolin is composed of 17 amino acids and is responsible for the pearl’s lustrous shine. In addition, the powder is naturally rich in trace minerals – notably calcium, magnesium, zinc, iron, potassium, and copper. These minerals and amino acids make it a highly nutritive supplement.
  • Functional Benefits
    Traditionally, pearl powder has been used as a beauty and health tonic. The conchiolin protein is often touted as a “beauty protein,” as historically some of the world’s renowned beauties (e.g. in ancient China and Egypt) consumed pearl to support youthful skin and overall vitality. Scientifically, conchiolin’s amino acids may support skin cell metabolism and hydration (though more research is needed for definitive mechanisms). The high calcium content can also support bone health and nervous system balance. Notably, weight management benefits have been observed: in preclinical studies, supplementation with Akoya pearl powder led to a reduction in visceral fat accumulation. In one study, rats fed a diet supplemented with 5% pearl powder had significantly lower visceral (abdominal) fat compared to controls, suggesting an antiobesity effect. While human clinical data is limited, this finding supports the idea that pearl powder may aid metabolic health. There are no known direct effects on hormonal regulation specific to pearl powder; however, by providing essential minerals (like zinc and magnesium), it could indirectly support normal hormone and enzyme functions in the body. Overall, Akoya Pearl Powder is valued for its contribution to skin health (radiance, complexion) and general wellness through its unique protein and mineral profile.

ORGANOLEPTIC & SENSORY PROFILE OF AKOYA PEARL POWDER

  • Appearance & Texture
    Akoya Pearl Powder is a very fine, off-white powder with a silky texture. It is produced in ultra-fine form (the particle size is on the order of a few microns), so it feels smooth rather than grainy.
  • Taste & Odor
    The powder is virtually tasteless and odorless. There is no fishy or ocean smell – any slight briny scent that might come from the pearl’s marine origin is eliminated during the cleaning process. Because the recommended dose is only 20 mg, such a small quantity would not impart any noticeable flavor or texture to a finished product. Even at higher doses, the taste is neutral enough that it can be easily masked if combined with other ingredients.
  • Solubility
    Pearl powder is not water-soluble. If added to liquids, it will disperse as a suspension. It can be taken by mixing into a beverage or smoothie, but you will notice a slight sediment. For a completely smooth beverage product, formulating with pearl powder might require keeping it suspended (for example, in a shake or using a thickening agent) or simply advising the consumer to stir before drinking. Because of this, Akoya Pearl Powder is most commonly put into capsules or tablets for supplementation, or used in powder blends that are meant to be ingested (like a spoonful in yogurt or a smoothie where a slight texture is acceptable).

APPLICATION & DOSAGE OF AKOYA PEARL POWDER

  • Recommended Dose
    The suggested daily intake of Akoya Pearl Powder is 20 mg per day. This dose is based on the manufacturer’s recommendation to achieve noticeable benefits for skin and health over time. Despite the seemingly small quantity, pearl powder’s effects are cumulative; consistent daily use is key (for example, in beauty supplement regimens, one might take 20 mg daily for several months). It’s worth noting that higher doses are also safe (pearl powder is essentially like a calcium supplement), but exceeding the recommended amount is usually unnecessary for cosmetic benefits. For reference, 20 mg of pearl powder contains roughly 7–8 mg of elemental calcium along with the conchiolin protein and trace minerals.
  • Forms of Use
    Akoya Pearl Powder is quite versatile:

Capsules/Tablets. Most commonly, it is encapsulated in beauty supplement capsules. For example, a capsule might contain 20–50 mg of pearl powder along with other skin supporting nutrients. Many Japanese and Chinese beauty supplement brands include pearl powder in their formulations for skin brightening and anti-aging.

Powder Blends. It can be included in nutritional powders or drink mixes (e.g., a collagen drink mix or a superfood blend). Given its insolubility, it works best in mixes that can be shaken or stirred well. Some contemporary wellness brands have started adding pearl powder to protein shakes and “beauty latte” powders for its mineral content and mystique as a traditional beauty ingredient.

Functional Foods. Less commonly, pearl powder can be added to foods (there are examples in Asia of pearl powder chocolates or cookies marketed for beauty). It can also be used in chewable tablets or lozenges.

  • Examples
    As this ingredient has a long history in Eastern health and beauty, numerous products utilize it. For instance, The Ginza (a high-end Japanese brand) has in the past included pearl powder in some of its beauty supplements. Likewise, in Traditional Chinese Medicine shops, pure pearl powder is sold as a tonic. Modern examples include capsule supplements in Japan that combine Akoya Pearl Powder with collagen or vitamins for skin health. One of our partners in Japan produces a “pearl collagen drink” where a small amount of pearl powder is mixed with marine collagen peptides in a ready-to-drink vial. These examples illustrate the flexibility of the ingredient – it can be a standalone capsule product or part of a complex formulation.
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What is Conchiolin?

BASIC INFORMATION

Conchiolin is a fibrous, insoluble structural protein that forms the organic basis of mollusk shells. It is secreted by the mollusk’s mantle and acts as a natural “cement,” binding together calcium carbonate crystals (aragonite) to build the shell’s hard structure. In nacre (mother-of-pearl), conchiolin layers make up only about 4–6% by weight, yet they play a crucial role: they separate and hold together aragonite crystal layers, which causes the beautiful iridescent luster of pearls. Chemically, conchiolin is a scleroprotein (an albuminoid) rich in amino acids like glycine, arginine, valine, and lysine. It is notably tough and resistant to water and mild acids, similar in character to keratin or collagen, providing durability and resilience to shells.

HISTORY OF CONCHIOLIN

Humans have valued the effects of conchiolin-containing substances (like pearls) for centuries, especially in traditional medicine. Pearl powder (which naturally contains conchiolin and minerals) has been used in Chinese medicine for over a thousand years for both beauty and health – treating skin ailments, strengthening bones, and calming the mind. Ancient texts and practices describe pearl or shell preparations used for improving complexion and treating ailments such as palpitations, insomnia, and epilepsy. Scientifically, the organic matrix of shells was first recognized in the 19th century, and the term “conchiolin” (from conch- meaning shell) was coined around 1865–1870 to describe this shell protein. Early researchers discovered that even after dissolving the mineral portion of a shell, a resilient organic framework remained – this was conchiolin, which provided insight into how shells are formed and why they are so strong.

PROPETIES AND FUNCTIONS

Conchiolin is an insoluble, collagen-like protein that gives shells both strength and flexibility. In the shell-forming process, mollusks deposit alternating layers of conchiolin and calcium carbonate; the conchiolin layers impart toughness and prevent brittleness by holding mineral layers together. This unique layered structure (organic protein alternating with mineral) results in a composite material that is remarkably strong and somewhat resistant to acids and heat. Conchiolin itself is comparable to other structural proteins (scleroproteins) in animals: it’s analogous to keratin (found in skin and hair) in that it contributes to hardness and protective function. Notably, conchiolin is responsible for a pearl’s inner glow – the thin conchiolin films between crystal layers create optical interference, giving pearls their iridescence. Biologically, the proteins in conchiolin also guide mineralization: they influence the formation of aragonite crystals (size, shape, orientation), essentially directing how the shell grows. Modern uses leverage these properties: when hydrolyzed (broken into smaller peptides), conchiolin becomes water-soluble and is used in supplements and cosmetics for its moisturizing and regenerative effects. It contains 17 types of amino acids and when ingested or applied, these amino acids can support skin and hair structure similar to dietary collagen.

CONCHIOLIN-CONTAINING PRODUCTS AND INTAKE

In a typical diet, conchiolin itself is not commonly encountered – one would have to actually consume parts of shells or pearls to intake this protein. Therefore, the main sources are specialized supplements and traditional remedies:

  • Pearl Powder
    Finely milled powder of pearls (or mother-of-pearl shells) is a popular supplement in Traditional Chinese Medicine and modern nutraceuticals. High-quality pearl powder provides conchiolin proteins along with calcium and trace minerals. It is taken orally in capsules or mixed into drinks. This supplement is prized for skin beauty and calming effects, and it has been used historically to treat ulcers and improve overall vitality.
  • Mother-of-Pearl (Nacre) Extract
    Some bone and joint health supplements contain nacre powder (from oyster or mussel shells) because of its calcium content and organic matrix. These nacre capsules supply calcium in a highly bioavailable form, plus conchiolin and collagen-like proteins that together support bone regeneration. Studies have shown that mother-of-pearl’s combination of calcium and conchiolin matrix is more effective for bone health than plain calcium carbonate. Such supplements are typically taken as 1–2 capsules per day.
  • Oyster Shell Calcium
    Oyster shells are about 95% calcium carbonate and contain a small fraction of conchiolin. Powdered oyster shell tablets are used as inexpensive calcium supplements. While their primary benefit is calcium for bones and teeth, they do incidentally provide trace conchiolin protein and marine minerals. (Manufacturers often purify oyster calcium; the residual conchiolin is minimal and not usually a selling point.)

INTAKE TIMING

Conchiolin-containing supplements are generally advised to be taken by mouth along with meals. Taking pearl or nacre powder with food (or a source of vitamin D) can enhance calcium absorption and reduce any stomach discomfort. For example, a common regimen for nacre capsules (for osteoporosis prevention) is one capsule daily with a meal, over a prolonged period. Since some people use pearl powder for its calming effects, it can be taken in the evening to help with relaxation and sleep, though traditional usage also allows it in the morning for daytime health support. Consistency is key: benefits (especially for bones or skin) accrue over weeks or months.

Conchiolin Effects and Health Benefits

Conchiolin (as found in pearl or shell powders) has a range of biological effects when taken as a supplement. These effects are a combination of the protein’s direct action and the accompanying minerals and amino acids that come with it. Key reported benefits include:

ENHANCES SKIN COLLAGEN AND ELASTICITY

Conchiolin is often called “pearl protein” for its skinbeautifying properties. It has been shown to promote healthy collagen production in the skin, which helps maintain firmness and reduce wrinkles. In fact, conchiolin’s amino acid profile is similar to that of keratin, a protein essential for skin and hair. By providing building blocks like glycine and proline, it can improve skin hydration, boost cell metabolism, and repair damaged cells. The result is often reported as increased skin suppleness and fewer fine lines. Users of pearl supplements often notice a “pearly” glow to their complexion – indeed, conchiolin was the component that gave pearls their luminescence, and in the skin it can support a radiant, smoother appearance.

EVENS SKIN TONE AND REDUCES PIGMENTATION

Another remarkable effect is skin brightening. Conchiolin has an ability to inhibit melanin synthesis, thereby fading dark spots and promoting a more even skin tone . Scientific studies support this depigmenting action: a 2023 in vitro study found that hydrolyzed conchiolin protein from pearls significantly suppresses tyrosinase activity (the enzyme responsible for melanin production) and downregulates key melanogenesis genes, resulting in lower melanin content in skin cells . This means conchiolin can help lighten hyperpigmentation and age spots. In traditional beauty remedies, pearl powder was used to lighten and brighten the complexion – modern science confirms that conchiolin in pearl can indeed act as a gentle skin whitener by modulating pigment production. Over time,  supplementation may lead to a visibly more even, luminous skin tone .

PROVIDES ANTIOXIDANT AND ANTI-AGING PROTECTION

Pearl-based supplements have notable antioxidant effects. They have been found to boost levels of the body’s key antioxidant enzymes, including superoxide dismutase (SOD) and glutathione, which protect cells from oxidative damage . By raising SOD and glutathione activity, conchiolin helps defend against free radicals and may slow down cellular aging and inflammation. This antioxidant property also contributes to preventing the formation of excess melanin (which can cause freckles and discoloration) . In animal studies, pearl powder showed anti-aging effects partly through stimulation of fibroblast  activity (cells that produce collagen) . It also exhibited anti-inflammatory and immunomodulatory actions, likely due to its magnesium and amino acid content . Overall, conchiolin’s presence in pearl powder makes it a rejuvenating supplement – protecting DNA from oxidative stress , supporting detoxification, and helping the body maintain youthful function.

STRENGTHENS BONES AND TEETH

Conchiolin-containing nacre has a significant impact on bone health. The combination of the organic matrix with calcium and trace minerals in mother-of-pearl can stimulate bone formation. Research in osteoporotic animal models found that diets supplemented with nacre powder (which includes conchiolin proteins) prevented bone loss far more effectively than calcium alone . The nacre-supplemented group maintained higher bone density and lower bone resorption, indicating a protective, strengthening effect on bone tissue . Scientists attribute this to bioactive conchiolin peptides and proteins in nacre that signal bone-building cells (osteoblasts) to function better . In practical terms, supplements derived from pearl or shell can help increase bone mineral density, promote new bone growth, and improve the quality of bone matrix. They are used to support conditions like osteoporosis, fracture healing, and even dental health (the same nacre components can strengthen dentin and periodontal structures) . For example, clinical feedback on mother-of-pearl capsules has shown benefits in osteoporosis management, periodontal (gum) health, and osteoarthritis symptoms . Thus, conchiolin is a key part of why “pearl calcium” is considered more than just calcium – it’s a holistic bone booster.

ACCELERATES WOUND HEALING AND TISSUE REPAIR

Conchiolin promotes regeneration of soft tissues as well. Experiments have demonstrated that pearl extracts can speed up wound healing by enhancing fibroblast migration and activity. In one study, a pearl extract tripled the movement of human fibroblast cells and increased their production of collagen, which is crucial for wound closure and skin repair . The presence of conchiolin and other pearl proteins is believed to stimulate fibroblasts to produce collagen fibers (with an observed increase in collagen type III, which is important in early wound healing) . This leads to faster regeneration of skin and perhaps other connective tissues. Traditional medicine has long used mother-of-pearl for its “tissue growing” properties – for instance, finely ground shell was applied to wounds or taken for peptic ulcers to help heal the mucosal lining . Modern findings support that conchiolin peptides can aid tissue regeneration, making them beneficial for healing skin injuries, and possibly for improving skin elasticity and reducing scar formation.

CALMS THE NERVES AND IMPROVES SLEEP

A well-documented traditional use of pearl (and thus conchiolin) is its sedative and calming effect on the nervous system. Historical texts describe powdered pearl as a remedy for palpitations, anxiety, and insomnia . Modern analysis suggests this is partly due to magnesium in pearl and the influence of conchiolin on neurotransmitters. 37 338 Pearl powder supplementation has been shown to elevate levels of GABA in the brain – GABA is an inhibitory neurotransmitter that produces a relaxing, anti-anxiety effect . By supporting GABA and even serotonin pathways, pearl (with conchiolin and magnesium) can help alleviate stress, ease nervous tension, and promote better sleep quality . Users often report improved sleep and a sense of calm when taking such supplements. Thus, conchiolin’s effect extends to mood support: it is used to “calm the shen” (spirit) in Chinese medicine terms, correlating to reduced anxiety and a more stable mood. This makes conchiolin-containing supplements attractive for people dealing with stress, restlessness, or mild insomnia as a natural calming agent.

BOOSTS ENERGY AND REDUCES FATIGUE

Interestingly, while calming, conchiolin doesn’t sedate in a negative way – it can simultaneously support overall vitality. Because pearl/nacre provides a spectrum of amino acids and trace minerals, it has an anti-fatigue and tonic effect on the body . In supplements given to athletes or the elderly, mother-of-pearl has been noted to improve energy levels and aid in post-exercise recovery . The bioavailable minerals (like calcium, magnesium, potassium) and protein components help reduce muscle fatigue and support muscle and nerve function. For older adults or those who are overworked, pearl supplements are said to help maintain energy and reduce exhaustion . This dual action – calming the mind while sustaining physical energy – reflects why it’s considered an adaptogenic substance in some wellness circles. It can help the body adapt to stress and recover, without overstimulation.

SUPPORTS IMMUNITY AND GUT HEALTH

Conchiolin’s amino acids (such as aspartic and glutamic acid) also have roles in immune function. Animal studies indicate that pearl powder can modulate immune responses and exhibit mild immunostimulatory effects . Antioxidant amino acids in conchiolin may enhance the immune system by protecting immune cells from oxidative stress . Additionally, traditional use of conchiolin-containing powders for ulcers suggests a benefit to gastrointestinal health. In TCM, pearl powder has been used internally to help heal gastric and duodenal ulcers and mouth sores . The soothing, restorative effect on mucous membranes could be due to the protein matrix forming a protective coating and promoting tissue repair (much like it does in wounds). While more human research is needed, these supplements are sometimes recommended as a complementary approach for those with minor ulcerations or inflammatory conditions of the gut, in addition to standard medical care.

Each of the above effects is supported by historical use or scientific studies, as cited. It’s important to note that many conchiolin benefits have been observed in cell or animal studies; human clinical data is still emerging. Individuals may experience varying results.

Conchiolin Supplements Are Recommended For:

  • Individuals with Osteoporosis or Bone Loss Risk
    Middle-aged and older adults, especially post menopausal women, who want to improve bone density naturally may consider nacre or pearl supplements . The unique combination of calcium and conchiolin in these supplements has been shown to support bone strength and reduce fracture risk.
  • People Seeking Healthier Skin and Hair
    Those concerned with skin aging, dryness, hyperpigmentation, or weak hair/nails can benefit from the collagen-boosting and hydrating effects of pearl powder . It’s often recommended as a beauty supplement to maintain youthful skin, reduce wrinkles, and give a radiant complexion.
  • Athletes and Active Individuals
    Because of its remineralizing and recovery benefits, conchiolin (in mother-of-pearl) is suggested for athletes or anyone doing regular physical training. It helps in muscle recovery and combating fatigue by replenishing minerals and supporting tissue repair . It can be a natural alternative or complement to standard calcium/magnesium supplements for those with high physical demands.
  • Those with Stress, Anxiety or Sleep Troubles
    People experiencing anxiety, high stress, or insomnia might try pearl supplements for their mild calming and sedative effects . It’s recommended for individuals who prefer a natural remedy to help with nerve tension, improve sleep quality, or support mood balance. (For example, students under stress or adults with hectic lifestyles sometimes use it as a calming tonic.)
  • Individuals with Mineral Deficiencies
    Anyone with a diet low in calcium or trace minerals (due to dietary restrictions or poor nutrition) could use conchiolin-containing products as a mineral 542 boost. The bioavailability of calcium from pearl/nacre is high – it’s absorbed about twice as efficiently as standard calcium carbonate . Thus, it’s recommended for people who need gentle calcium supplementation (like those who can’t tolerate regular calcium tablets).
  • Support for Ulcers or Mucosal Health (Traditional Use)
    In historical and alternative practice, pearl powder is given to people with recurrent mouth ulcers or sensitive gastric mucosa . If someone has mild gastric ulcer issues and is looking for a supplementary remedy (alongside medical treatment), practitioners of Ayurveda or TCM sometimes recommend pearl preparations to soothe and heal the mucous membranes.
  • Elderly or Convalescent Individuals
    The elderly, or those recovering from long illnesses, may take conchiolin-rich tonics to regain strength. In particular, tired, overworked individuals or convalescents are advised to use mother-of-pearl supplements as an anti-fatigue and revitalizing agent, to improve energy and maintain muscle and bone mass.

Information on Conchiolin Research

1] Pearl Powder—An Emerging Material for Biomedical Applications: A Review - PMC.
https://pmc.ncbi.nlm.nih.gov/articles/PMC8197316/

2] Pearl extract enhances the migratory ability of fibroblasts in a wound healing model.
https://pubmed.ncbi.nlm.nih.gov/23043617/

3] Hydrolyzed Conchiolin Protein (HCP) Extracted from Pearls Antagonizes both ET-1 and α-MSH for Skin Whitening.
https://pubmed.ncbi.nlm.nih.gov/37108635/

4] Protective Effect on Bone of Nacre Supplementation in Ovariectomized Rats.
https://pubmed.ncbi.nlm.nih.gov/36111203/

Got Questions? We've Got Answers

Frequently Asked Questions

  • What is the daily dose of Akoya pearl powder?

    The recommended daily intake is 20 mg. This amount is sufficient to deliver the functional benefits of calcium and conchiolin. It can be taken alone or blended into beauty formulas, capsules, or drinks.

  • Can I combine pearl powder with collagen?

    Yes, absolutely. Pearl powder pairs well with ingredients like collagen, placenta extract, and elastin peptides. Together, they enhance skin elasticity, hydration, and inner glow — ideal for advanced anti-aging or nutricosmetic formulas.

  • Is pearl powder safe during pregnancy?

    Every pregnancy is unique, and nutritional needs may vary. While Akoya pearl powder is a natural source of calcium and amino acids, we recommend consulting a healthcare provider before using any supplement during pregnancy.

  • Why is Japanese pearl powder better than Chinese?

    Japanese Akoya pearl powder contains significantly more conchiolin — the bioactive protein responsible for skin glow, regeneration, and cellular repair. As shown in microscopic imaging, Akoya pearls have a higher density of conchiolin layers, giving them superior bioactivity and mineral structure. This makes Japanese pearl powder a premium choice for beauty and wellness applications.

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